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Modifying the carrier surface with targeting molecules such as aptamers or functional peptides can improve local drug retention and specificity in diseased cartilage or pathological synovial cells, while reducing potential adverse effects from systemic exposure

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NCOA4 links iron bioavailability to DNA metabolism

Its unusual stability in acidic environments sets it apart from conventional peptides: the literature has reported a meaningful half-life at pH 2 and resistance to digestive proteases, making it a unique subject of study within the regenerative research peptide class

The metabolism of carcinoma Cells1

Therefore, many chemotherapeutic drugs and targeted therapies are unable to effectively penetrate the BBB, limiting their efficacy in treating GBM